Data-driven detection of concerning SARS-CoV-2 variants months in advance

Since the start of the SARS-CoV-2 pandemic, several variants of the virus have developed into Variants of Concern (VOCs), as classified by the World Health Organization (WHO). VOCs are virus variants that are predicted or known to cause large waves of infections due to their altered phenotypic characteristics and with a risk of altering disease severity, reducing vaccine effectiveness or otherwise leading to increased burden of health care systems.

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