Research

Pregnant women undergo all kinds of medical checks. This is to monitor the health of both the mother and child and to detect potential abnormalities as early as possible.... Read more

From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body's typically efficient DNA repair machinery and potentially affecting our health and well-being.... Read more

Researchers have long focused on the STING (Stimulator of Interferon Genes) pathway as a way to harness the immune system's natural defenses against cancer. This pathway, which plays a key role in helping the body defend against potential pathogens, can be leveraged to trigger an innate immune response that targets... Read more

Excessive physical exercise, especially without adequate rest, can damage the human body in various ways. In severe cases, it can progress to overtraining syndrome, which is characterized by decreased performance and appetite, chronic fatigue, muscle pain, increased injuries, and changes in the immune system and metabolism.... Read more

By creating artificial aging in mice, researchers at Lund University in Sweden have been able to track the formation of aneurysms in the walls of blood vessels.... Read more

Bite the inside of your cheek, and the wound may vanish without a trace in a couple of days. A preclinical study co-led by Cedars-Sinai, Stanford Medicine and the University of California, San Francisco (UCSF), has discovered one secret of this disappearing act. The findings, if confirmed in humans, could... Read more

In August 2024, the World Health Organization declared a second "Public Health Emergency of International Concern" for mpox. The current outbreak in Africa is driven mainly by the clade I variant, with multiple countries reporting their first-ever mpox cases of this more severe strain.... Read more

A new study by investigators from Europe, including the Netherlands and the United Kingdom (UK), has shed light on significant ethical, administrative, regulatory, and logistical (EARL) hurdles in delivering multinational randomized clinical trials. The research was the first to comprehensively quantify these barriers for an international platform trial and emphasizes... Read more

A study by researchers at Rutgers Health has uncovered a way to precisely identify and target trauma sites in the body within minutes of injury. The findings, published in the journal Med, could revolutionize emergency care by enabling real-time diagnostics and site-specific treatments delivered within minutes of injury.... Read more

Candida auris is a dangerous fungal pathogen that has become a global health concern. It spreads easily in health care settings and can cause life-threatening infections, especially in patients with weakened immune systems. Alarmingly, it is often resistant to multiple antifungal drugs, making treatment difficult.... Read more

Cancer cells have the capacity to multiply rapidly. The aggressive cancer cells undergo conversion from their tightly connected epithelial state into a mesenchymal state, which lacks contact restrictions and spreads easily to other parts of the body. Such epithelial-to-mesenchymal plasticity also makes the cancer cells resistant to elimination by anticancer... Read more

A rare cell in the lining of lungs is fundamental to the organ-wide response necessary to repair damage from toxins like those in wildfire smoke or respiratory viruses, Stanford Medicine researchers and their colleagues have found. A similar process occurs in the pancreas, where the cells, called neuroendocrine cells, initiate... Read more

A research team led by Professor Koji Eto revealed that disruptions of the KCNN4 potassium channel impair mitochondrial function and cytoskeletal organization in megakaryocytes, leading to reduced platelet production, thus highlighting a key regulatory mechanism in thrombopoiesis.... Read more

The innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component of this system are pattern recognition receptors, which recognize non-self RNA—such as that from viruses and bacteria—and trigger an immune response.... Read more

Assessing the distribution of a medication in the brain is critical for the treatment of a vast range of neurological disorders, especially conditions such as Parkinson's and Alzheimer's diseases. To that end, scientists in the United States and Sweden are developing a method to image therapeutic antisense oligonucleotides in the... Read more