Research

Researchers at the University of East Anglia have solved an 80-year-old medical mystery of the cause of kidney damage in children, which can be fatal in babies.... Read more

Dietary restriction (DR) is a highly effective and reproducible intervention that prolongs longevity in many organisms. The molecular mechanism of action of DR is tightly connected with the immune system; however, the detailed mechanisms and effective downstream factors of immunity that mediate the beneficial effects of DR on aging remain... Read more

A new blood test that can identify progression of osteoarthritis in the knee is more accurate than current methods, providing an important tool to advance research and speed discovery of new therapies.... Read more

A DZHK research team at the University Medical Center Mainz has discovered a new signaling pathway of the coagulation system that controls scar formation after a heart attack. If this signaling pathway could be inhibited, heart attacks could heal with less subsequent damage.... Read more

For a long time, cancer genetics and epigenetics researchers have been focusing on alterations in genes and proteins to understand what makes a cell turn cancerous and become malignant. In the nucleus of the cell, there is crosstalk between highly complex gene networks, controlled by small dispersed regulatory elements through... Read more

About 196 million women worldwide suffer from endometriosis, a condition that typically causes pelvic pain and infertility. Endometriosis develops when lining inside the womb grows attached to surrounding tissues, such as the intestine or the membrane lining the abdominal cavity, causing bleeding, pain and other symptoms. Despite decades of research,... Read more

New research published in The FASEB Journal indicates that e-cigarettes can cause cellular and molecular changes in the lungs. Specifically, prolonged inhalation of e-cigarette aerosols by mice caused changes in the animals' pulmonary immune cell composition and altered gene and protein levels in the lungs.... Read more

In 2019 Dr. Stephen Withers and colleagues at the University of British Columbia identified a series of enzymes that can be used to modify the chemical structure of a sugar antigen on the surface of blood cells, thereby converting a Type A blood cell to a Type O blood cell—the... Read more

The fight-or-flight response evolved to keep us safe from predators, but it can sometimes cause us to overreact in modern life when we don't face the same dangers we once did. Now, researchers from Japan have found that a common panic response may actually reduce our ability to deal with... Read more

Traumatic brain injury is a leading cause of epilepsy, a chronic neurological disorder characterized by recurrent seizures that affects around 50 million people. A research team led by Bret Smith, professor and head of the Department of Biomedical Sciences, discovered specific neuronal processes that could help advance future preventative treatments... Read more

A new study from University of Galway has found high death rates in weaning intensive care patients from ventilation.... Read more

A team of researchers at the University of Vienna has found evidence showing that listening to music when stressed can boost a person's mood and help them relax. In their paper published on the JAMA Network Open site, the group describes an experiment they conducted with volunteers under stress caused... Read more

Many cardiovascular diseases, such as atherosclerosis, or "hardening of the arteries," correlate to mitochondrial dysfunction and endothelial impairment in the tissues of the heart and blood vessels. Despite a significant improvement in therapies to treat cardiovascular disease, there is an unmet need to investigate mitochondria as a therapeutic target.... Read more

A study by chemists at the University of Chicago has uncovered a new key step in the process that HIV uses to replicate itself.... Read more

For anyone who has taken Biology 101, the concept of apoptosis—programmed cell death—is taught early in the course. You can't understand the life cycle of a cell without learning how they die.... Read more