Research

A team of biologists affiliated with multiple institutions in China, working with a colleague in the U.S., has found that giving cynomolgus monkeys the diabetes drug metformin can reduce aging in multiple organs, including the brain.... Read more

As society ages, the number of patients with heart failure is rapidly increasing. Excessive growth of fibrotic tissue in the heart, known as fibrosis, is associated with the progression of heart failure. A group from the Nagoya University Graduate School of Medicine in Japan has found an enzyme protein kinase... Read more

AMeD syndrome is a severe genetic condition found in children that presents with accelerated aging, global developmental delay and bone marrow failure, progressing to myelodysplastic syndrome and acute myeloid leukemia.... Read more

Harvard stem cell biologists have pioneered a groundbreaking 3D organoid culture method for generating large numbers of adult skeletal muscle satellite cells, also known as muscle stem cells, in vitro.... Read more

A study led by researchers at the University of Colorado Anschutz Medical Campus reveals that stress-induced changes in sperm motility occur after a stressful event, rather than during it and improves sperm performance. The discovery is essential in understanding how stress impacts the reproductive process to improve fetal development outcomes.... Read more

Investigators are constantly aiming to identify new therapeutic approaches for regenerative medicine. Recent strategies have focused on harnessing the power of the body's own tissue healing and repair mechanisms, including anti-inflammatory signaling molecules and immune cells.... Read more

Four researchers working in the United States are sharing a $1 million prize from a Portuguese foundation for their work on how the human brain distinguishes faces, shapes and colors.... Read more

In the midst of America's growing opioid crisis, a much healthier alternative to long-term pain management is emerging—one affectionately known as "the cuddle hormone," or oxytocin.... Read more

Honestly prescribed placebo treatments for chronic back pain (CPB) led to significant improvements in pain alleviation with lasting results, according to a new study out today in JAMA Network Open.... Read more

Cancer cells are driven by the same imperative guiding all living things: to grow, survive and reproduce. Although cancer's evolutionary underpinnings have been recognized since the 1950s, clinicians have been slow to apply the lessons of evolution to the fight against this deadly disease, which remains the second-leading cause of... Read more

A multi-institutional team of ovarian biologists and other reproductive specialists reports that putting an oocyte from an older mouse into the follicle of a young mouse can rejuvenate the oocyte, allowing for the release of an egg on par with those of a young mouse. The results are published in... Read more

Many clinical trials of new cancer drugs may be inappropriately excluding some people with "Duffy-null phenotype," a trait found predominantly in people of African or Middle Eastern descent, researchers at Dana-Farber Cancer Institute and Queen Mary University of London report in study published in JAMA Network Open.... Read more

Excess abdominal fat is associated with widespread chronic pain, particularly in women, finds the first study of its kind, published in the open access journal Regional Anesthesia & Pain Medicine.... Read more

Violent blows or jolts to the head can cause traumatic brain injury (TBI), and there are currently about five million people in the U.S. living with chronic neurodegeneration and related impairments due to TBI. In addition to cognitive and mental health impairment, chronic neurodegeneration may also contribute to why TBI... Read more

A Phase III study comparing tusamitamab ravtansine with docetaxel in patients with advanced non-squamous non-small cell lung cancer (NSCLC) previously treated with platinum-based chemotherapy and immunotherapy (in combination or sequential), whose tumors highly expressed CEACAM5, was presented at the International Association for the Study of Lung Cancer 2024 World Conference... Read more