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Researchers have developed a novel rat model that closely replicates the pathological features and physiological changes associated with human chronic obstructive pulmonary disease (COPD)-associated cor pulmonale. This model exhibits key characteristics, including chronic lung inflammation, […]

Hypertension is a major public health concern, affecting millions worldwide and increasing the risk of heart disease, stroke, and kidney failure. It is typically characterized by persistent high blood pressure, which can result from multiple […]

As the world’s population ages, intervertebral disk degeneration (IDD) has become a major medical issue, causing chronic lower back pain and mobility issues that diminish the quality of life for millions. The study from the […]

The Trump administration’s freeze of more than $2 billion in federal research grants to Harvard has disrupted work in a number of areas, including efforts to ensure the rights and safety of patients who take […]

Exposure to air pollution–derived ultrafine particles alters gene transcription by epigenetic mechanisms, a new study shows. The changes affected, for example, cellular survival.This post was originally published on this site

Conflicting findings in environmental epidemiology have long stalled consensus on the health effects of toxic chemicals. A new study by Columbia University Mailman School of Public Health published in the American Journal of Epidemiology suggests […]

For patients with cancers harboring certain genetic defects, the first-in-class targeted therapy RO7589831, which targets the DNA repair enzyme Werner helicase, demonstrated early signals of efficacy and was generally well-tolerated, according to Phase I trial […]

Amyotrophic lateral sclerosis (ALS) is a disease that destroys the nerves necessary for movement. About 30,000 people in the United States are affected, and doctors still don’t know what causes it. To lay the groundwork […]

The restricted mean survival time (RMST) analysis technique was introduced in health care research about 25 years ago and since then has become widely used in economics, engineering, business and other professions.This post was originally […]

Each year, more than 11 million people worldwide suffer serious life-changing burns, affecting both adults and children. The largest-ever project of its kind—the Priorities in Global Burns Research partnership, led by the University of Bristol—has […]