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A new experimental infection model in flies offers a fast and cost-effective way to test drugsResearchers at the Germans Trias i Pujol Research Institute and Hospital have characterized and developed a new study model using Drosophila that will enable the evaluation of various infectious agents.... Read more
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Transparency and reporting characteristics of randomized controlled trials with Chinese herbal medicineIn 2017, the CONSORT-CHM Formulas 2017 extension was introduced to enhance the reporting transparency of randomized controlled trials (RCTs) involving Chinese herbal medicine (CHM) formulas. This development aimed to detail the rationale, design, analysis, and interpretation of CHM formula interventions, thereby improving clinical trial execution and advancing traditional Chinese medicine... Read more
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Study examines development of early COPD in ages 30 to 55Researchers are exploring how small airway abnormalities in younger smokers could help identify who is at risk of developing COPD and establish how the chronic lung disease progresses. The article is published in the September 2024 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation.... Read more
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Steroid and surfactant mix fails to impact bronchopulmonary dysplasia in preterm infantsResearch led by the Royal Women's Hospital, Australia, has found that early intratracheal administration of budesonide mixed with surfactant may have little to no effect on improving survival free of bronchopulmonary dysplasia (BPD) in extremely preterm infants.... Read more
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Treatment advances and predictive biomarkers stand to improve bladder cancer careRecent advances in bladder cancer treatments may offer hope of curative care to more patients, including those with high-risk localized, muscle-invasive disease, according to an editorial published in the New England Journal of Medicine.... Read more
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Air pollution linked to increased miscarriage riskA team of medical and environmental researchers at the Medical School of Yan'an University, working with a colleague from Yan'an University Affiliated Hospital, has found a link between spontaneous miscarriages and exposure of pregnant people to certain types of air pollution.... Read more
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Potential single-dose smallpox and mpox vaccine moves forwardVaccines that prevent smallpox and mpox come in two varieties. One uses a single shot of a live virus but carries the risk of serious side effects; the other, which is newer and made with replication deficient virus, has fewer side effects but requires two doses.... Read more
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Researchers discover why taking a mushroom supplement slows or prevents prostate cancer from getting worseResearchers at City of Hope now understand why taking an investigational white button mushroom supplement shows promise in slowing and even preventing prostate cancer from spreading among men who joined a phase 2 clinical trial studying "food as medicine."... Read more
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Research shows non-hallucinogenic marijuana constituent increases sleep in ratsResearch by scientists at the University of Sydney has identified a constituent in the cannabis plant that improves sleep. Their report is the first to use objective measures to show the component, known as cannabinol (CBN), increases sleep in rats.... Read more
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How immune cells 'sniff out' pathogens: Signaling study could speed up the search for new drugsImmune cells are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, or TLRs for short. But what signals activate TLRs, and what is the relationship between the scale and nature of this activation and the substance being detected?... Read more
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Study identifies top ten priorities for future research on reducing and stopping psychiatric medicationThe global consumption of psychiatric medication is increasing by 4% annually, with the greatest increase observed in antidepressant use. For people who wish to reduce and/or stop taking medication, there are many gaps and unanswered questions on how best to do this.... Read more
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Researchers analyze present, future of emergency consent in stroke trialsThe University of Cincinnati's Yasmin Aziz, MD, and Joseph Broderick, MD, coauthored an editorial published on Nov. 7 in the journal Neurology analyzing the current use and potential future of alternatives to traditional informed consent in acute stroke trials.... Read more
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Memories are not only in the brain, human cell study findsIt's common knowledge that our brains—and, specifically, our brain cells—store memories. But a team of scientists has discovered that cells from other parts of the body also perform a memory function, opening new pathways for understanding how memory works and creating the potential to enhance learning and to treat memory-related... Read more
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DNA sequencing reveals significant decrease in gut bacterial diversity during agingA new study has revealed that gut bacteria may play a key role in aging, and that specific microbes could be targeted to promote healthy aging.... Read more
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Mouse model demonstrates Chinese herbal medicine's potential in preventing dementiaAttempts to discover a breakthrough dementia drug might be drawing attention these days, but traditional medicinal products can offer hints for preventive medicine.... Read more