Research

Chemotherapy used to target and kill bladder cancer cells may trigger an inflammatory response that ultimately may make the cancer more resistant to treatment, according to new research from scientists at Houston Methodist.... Read more

All day long, our brains carry out complicated and energy-intensive tasks such as remembering, solving problems, and making decisions.... Read more

Imagine two people talking over a walkie-talkie set. Successful communication depends on them being tuned to the same frequency. If others try to communicate nearby, interference can occur, and important messages may be lost.... Read more

Human eggs are some of the most patient cells in the body, lying dormant for decades until needed. A study published in The EMBO Journal shows that the cells deliberately slow the activity of their internal waste disposal systems as they mature, most likely an evolutionary design which keeps metabolism... Read more

A new publication by two University of Cincinnati researchers contends that adjusting how researchers approach their statistical analysis has the potential to change the lives of children and adolescents struggling with mental health issues across the world.... Read more

Research presented today at the Society of NeuroInterventional Surgery's (SNIS) 22nd Annual Meeting included three studies that explored the differences in treatment and recovery options for patients across racial, gender and socioeconomic lines in a large telestroke network in Pennsylvania and a university medical center in Rhode Island.... Read more

Mayo Clinic researchers have discovered a key reason some cancer patients relapse after receiving chimeric antigen receptor T-cell therapy, or CAR-T cell therapy. Over time, the engineered immune cells age and lose their ability to fight cancer.... Read more

A research team led by Professor Takuya Yamamoto (Department of Life Science Frontiers) and Professor Yasuhiro Yamada at the University of Tokyo has developed a novel in vivo system that reveals how senescent cells behave in living tissues and influence aging through complex, heterogeneous mechanisms. The research is published in... Read more

A Finnish population study shows that signs related to Alzheimer's disease may already be found in the brain in middle age. In the future, blood-based biomarkers associated with Alzheimer's disease could allow earlier detection of the disease. This would allow preventive treatment to be targeted at the right individuals while... Read more

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody against the virus. Antigen in, antibody out.... Read more

Researchers from KU Leuven, the University of California Davis Medical Center, the University of Cologne, and over 20 collaborating institutions report that the antifungal olorofim demonstrated efficacy and tolerability in patients with invasive fungal disease who had exhausted most other treatment options.... Read more

The skin has two types of adult stem cells: epidermal and hair follicle. Their jobs seem well-defined: maintaining the skin, or maintaining hair growth. But as research from Rockefeller University has shown, hair follicle stem cells (HFSCs) can switch teams, pitching in to heal the skin when it receives an... Read more

A new study from the University of Colorado Anschutz Medical Campus has upended decades of neuroscience dogma, revealing that dopamine, a neurotransmitter critical for movement, motivation, learning and mood, communicates in the brain with extraordinary precision, not broad diffusion as previously believed. This groundbreaking research offers fresh hope for millions... Read more

Nerve cells are not just nerve cells. Depending on how finely we distinguish, there are several hundred to several thousand different types of nerve cells in the human brain, according to the latest calculations. These cell types vary in their function, in the number and length of their cellular appendages,... Read more

A team has made a major breakthrough in the field of three-dimensional (3D) imaging of large-scale biological tissues. They developed the world's fastest high-definition 3D imaging technology for the entire body of small animals at subcellular resolution, enabling efficient mapping of the fine architecture of the peripheral nervous system (PNS).... Read more