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Chemerin receptor structures disclose new mechanism of lipid metabolismChemerin is a key adipokine that regulates lipid metabolism and insulin sensitivity, and thus is involved in many metabolic diseases such as obesity and diabetes. In addition, it plays a critical role in inflammation as a chemoattractant adipokine by guiding immune cell trafficking to inflammatory sites.... Read more -
Population-specific genetic risk scores advance precision medicine for Han Chinese populationsResearchers at Academia Sinica have developed the first population-specific polygenic risk score (PRS) models for people of Han Chinese ancestry, achieving unprecedented accuracy in predicting risks for common diseases such as diabetes, heart disease, autoimmune disorders. The study, published in Nature on October 15, 2025, analyzed genomic and health data... Read more -
Research unveils new insights on face blindnessFor most of us, it happens automatically: we recognize a face in a split second. But for people with developmental prosopagnosia—also known as face blindness—recognizing people is a daily challenge.... Read more -
New on-switch for pain signaling pathway could lead to safer treatment and reliefResearchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead to safer, more effective treatments.... Read more -
Wearable health technology brings research closer to peopleAt the University of Oulu in Finland, researchers are exploring new ways to utilize microwave technology in monitoring and assessing health conditions. The results of experiments conducted with realistic models are promising.... Read more -
French scientists probe mRNA's potential to fight cancerInside a lab in the French city of Orleans, scientists are testing out the limits of molecules in our body called messenger RNA—best known for being used in COVID-19 vaccines—in the hopes of finding a breakthrough treatment for a particularly deadly cancer.... Read more -
Key protein for healing nerve damage reveals a dual roleNerve damage can be an unfortunate side effect from an accident, illness or even certain treatments, like chemotherapy. Fortunately, the peripheral nervous system can heal itself to a certain extent, albeit very slowly. Researchers are still trying to understand this natural healing process in order to improve it.... Read more -
Phase II clinical trial results show potential to shorten TB treatment timeNew clinical trial results presented by TB Alliance at the Union World Conference on Lung Health show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the potential to improve tuberculosis (TB) treatment when combined with pretomanid and linezolid in a treatment regimen known as "SPaL."... Read more -
NIH grant terminations leave thousands without access to care, study findsThousands of clinical trial participants lost access to important medical studies this year after the Trump administration terminated hundreds of National Institutes of Health (NIH) grants, according to new research published in JAMA Internal Medicine.... Read more -
Targeted protein degradation: A new way to combat harmful proteins in tumor cellsA new active substance attacks a key protein in tumor cells, leading to complete degradation. In cell experiments, this caused cancer cells to lose their protection and die. The active substance was developed by researchers at the Martin Luther University Halle-Wittenberg (MLU) and the University Medical Center Mainz. Other substances... Read more -
How cancer cells 'break through' tight tissue gapsAggressive cancer cells are masters of movement. When they spread through the body, they cause metastasis, which significantly reduces a person's chance of survival. For this spreading to take place, they can switch between different cell states—behaviors of cells—that move with different strategies.... Read more -
Bone marrow model built entirely from human cells can reduce animal testingOur body's "blood factory" consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types. Now, researchers have succeeded for the first time in recreating this cellular complexity in the laboratory using only human cells. The novel system could reduce the need for animal experiments... Read more -
Blood tests and sputum analysis help predict COPD exacerbation risksA research team from the LKS Faculty of Medicine at the University of Hong Kong (HKUMed) has highlighted recent advances in understanding and managing COPD, particularly in relation to its exacerbations. The key findings indicate that patients' risk profiles can be assessed by measuring blood eosinophil counts at various time... Read more -
Scientists identify two key targets of common cold virusScientists were pleased when they learned more about how the common cold gains a foothold in the body, identifying key cellular checkpoints that are important targets of the virus.... Read more -
Disrupting bacterial 'chatter' could tip the balance for better oral healthLike all living things, bacteria adapt to survive. Over time, bacteria have been developing resistance to common antibiotics and disinfectants, which poses a growing problem for health care and sanitation. However, many species of bacteria are beneficial and even essential for human health. What if there was a way to... Read more
