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Glucose helps T cells build cancer-fighting structures, not just provide energyFor cancer- and infection-fighting T cells, glucose offers far more than a simple sugar rush.... Read more
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Hidden receptors in fat cells reveal new sensing mechanism for metabolismResearchers from the University of Birmingham have uncovered a completely new mechanism by which fat cells (adipocytes) control how they store and release fat.... Read more
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Air pollution linked to higher risk of dementia and neurological diseaseAntonella Zanobetti was conducting groundbreaking research to examine links between exposure to environmental factors, such as pollution and heat, and deadly neurological and cardiovascular diseases. But three of her studies came to a halt with the Trump administration's mass cancelation of Harvard research grants in May.... Read more
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Study links reduced ribosome levels to vulnerability in developing brain cellsA team led by UT Southwestern Medical Center scientists has identified a specific stage of neurodevelopment when differentiating neural cells produce fewer ribosomes, which are responsible for making proteins. This subsequent drop in protein production, they report in Nature Cell Biology, helps explain why mutations that further affect ribosome production... Read more
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Beyond classic stress signaling: How mitochondrial stress softens the cell nucleus and alters cellular identityMitochondria are specialized structures within cells that are primarily responsible for energy production but that also play a key role in how cells respond and adapt to stress. When their function fails, particularly in energy-demanding tissues like brown fat, the entire organism must adapt.... Read more
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Bacterial cellulose-based dressing offers rapid bleeding control for burn wound careIn a study published in Advanced Materials, a research team developed an innovative bacterial cellulose (BC)-based hemostatic dressing that enables rapid and sustained bleeding control.... Read more
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Scientists identify shared biological roots of long COVID and chronic fatigue syndromeIn recent years, doctors and scientists are increasingly studying long-lasting illnesses that begin after someone recovers from an infection. Two of the most well-known examples are long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).... Read more
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Light-sensitive molecule boosts deep tissue imaging and cell control in miceBiomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have developed a technique that naturally increases the presence of a light-sensitive molecule throughout the body. This change makes it possible to both improve deep tissue imaging in areas like the brain and expand the capabilities... Read more
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Study involving turquoise killifish pinpoints key mechanism of brain agingAging and neurodegeneration are both known to disrupt the production of functional proteins in cells—a process called "proteostasis," or protein homeostasis. Brain cells in particular fall prey to proteostasis disruptions, which are linked to the accumulation of protein aggregates in neurodegenerative diseases.... Read more
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National drug trial shows early promise for treatment of rare blood cancerEncouraging early results from a SAHMRI-led clinical trial offer new hope to people diagnosed with chronic myelomonocytic leukemia (CMML), a rare and aggressive form of blood cancer.... Read more
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Global dementia research must reflect global diversityA major international research effort led by UNSW's Center for Healthy Brain Aging (CHeBA) is reshaping our understanding of dementia by addressing a longstanding gap in global health equity.... Read more
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Mouse diet could be messing with imaging accuracyAn innovative new study from researchers at the Center for Healthy Brain Aging (CHeBA), UNSW Sydney, reveals that something as simple as a mouse's dinner could be distorting critical preclinical imaging results.... Read more
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Synthetic torpor offers potential to redefine medicine, say researchersNature is often the best model for science. For nearly a century, scientists have been trying to recreate the ability of some mammals and birds to survive extreme environmental conditions for brief or extended periods by going into torpor, when their body temperature and metabolic rate drop, allowing them to... Read more
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How do our genes influence our sense of smell? Study finds sex-specific effectsHow we smell is not just a matter of taste—it's also influenced by our genes. An international team of researchers led by scientists from Leipzig University has conducted the largest genetic study to date on the human sense of smell. Researchers at the Institute for Medical Informatics, Statistics and Epidemiology... Read more
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With no need for sleep or food, AI-built 'scientists' quickly design nanobodies against SARS-CoV-2 variantsImagine you're a molecular biologist wanting to launch a project seeking treatments for a newly emerging disease. You know you need the expertise of a virologist and an immunologist, plus a bioinformatics specialist to help analyze and generate insights from your data. But you lack the resources or connections to... Read more