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Research

  • ISS researcher links bone loss in astronauts to stem cell changes in microgravity
    Mayo Clinic physician and researcher Dr. Abba Zubair's work combines two passions—medicine and space—for the benefit of astronauts and people on Earth. His research in space is yielding discoveries in cancer, stroke, bone loss and more.... Read more
  • Budget cuts threaten the future of biomedical research—and the young scientists behind it
    Over the last several months, a deep sense of unease has settled over laboratories across the United States. Researchers at every stage—from graduate students to senior faculty members—have been forced to shelve experiments, rework career plans, and quietly warn each other not to count on long-term funding. Some are even... Read more
  • A mathematical perspective offers insight into the placenta's role and functioning
    Pregnant women undergo all kinds of medical checks. This is to monitor the health of both the mother and child and to detect potential abnormalities as early as possible.... Read more
  • Change trackers: New consortium to catalog DNA mutations across human lifetime
    From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body's typically efficient DNA repair machinery and potentially affecting our health and well-being.... Read more
  • Researchers reveal key differences in STING inhibition between humans and mice
    Researchers have long focused on the STING (Stimulator of Interferon Genes) pathway as a way to harness the immune system's natural defenses against cancer. This pathway, which plays a key role in helping the body defend against potential pathogens, can be leveraged to trigger an innate immune response that targets... Read more
  • Study finds overtraining syndrome tied to increased PARP1 protein in muscles
    Excessive physical exercise, especially without adequate rest, can damage the human body in various ways. In severe cases, it can progress to overtraining syndrome, which is characterized by decreased performance and appetite, chronic fatigue, muscle pain, increased injuries, and changes in the immune system and metabolism.... Read more
  • New cell signaling pathway found to shield blood vessels from hypertension damage
    By creating artificial aging in mice, researchers at Lund University in Sweden have been able to track the formation of aneurysms in the walls of blood vessels.... Read more
  • Preclinical study unlocks a mystery of rapid mouth healing
    Bite the inside of your cheek, and the wound may vanish without a trace in a couple of days. A preclinical study co-led by Cedars-Sinai, Stanford Medicine and the University of California, San Francisco (UCSF), has discovered one secret of this disappearing act. The findings, if confirmed in humans, could... Read more
  • Using viral load tests to help predict mpox severity when skin lesions first appear
    In August 2024, the World Health Organization declared a second "Public Health Emergency of International Concern" for mpox. The current outbreak in Africa is driven mainly by the clade I variant, with multiple countries reporting their first-ever mpox cases of this more severe strain.... Read more
  • Study highlights major hurdles for multinational clinical trials in Europe
    A new study by investigators from Europe, including the Netherlands and the United Kingdom (UK), has shed light on significant ethical, administrative, regulatory, and logistical (EARL) hurdles in delivering multinational randomized clinical trials. The research was the first to comprehensively quantify these barriers for an international platform trial and emphasizes... Read more
  • A new identification method unlocks fast, targeted treatment for trauma injuries
    A study by researchers at Rutgers Health has uncovered a way to precisely identify and target trauma sites in the body within minutes of injury. The findings, published in the journal Med, could revolutionize emergency care by enabling real-time diagnostics and site-specific treatments delivered within minutes of injury.... Read more
  • Antifungal discovery offers hope against deadly drug-resistant infections
    Candida auris is a dangerous fungal pathogen that has become a global health concern. It spreads easily in health care settings and can cause life-threatening infections, especially in patients with weakened immune systems. Alarmingly, it is often resistant to multiple antifungal drugs, making treatment difficult.... Read more
  • Benzaldehyde blocks pancreatic cancer spread by disrupting key protein interactions
    Cancer cells have the capacity to multiply rapidly. The aggressive cancer cells undergo conversion from their tightly connected epithelial state into a mesenchymal state, which lacks contact restrictions and spreads easily to other parts of the body. Such epithelial-to-mesenchymal plasticity also makes the cancer cells resistant to elimination by anticancer... Read more
  • Rare lung cells trigger rapid repair after smoke or virus exposure in mice—a similar pathway may exist in humans
    A rare cell in the lining of lungs is fundamental to the organ-wide response necessary to repair damage from toxins like those in wildfire smoke or respiratory viruses, Stanford Medicine researchers and their colleagues have found. A similar process occurs in the pancreas, where the cells, called neuroendocrine cells, initiate... Read more
  • Unleashing potassium for better mitochondrial health and platelet biogenesis
    A research team led by Professor Koji Eto revealed that disruptions of the KCNN4 potassium channel impair mitochondrial function and cytoskeletal organization in megakaryocytes, leading to reduced platelet production, thus highlighting a key regulatory mechanism in thrombopoiesis.... Read more

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