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Experts call for ban on fossil fuel-linked medical researchAn investigation published by The BMJ today reveals the extent of fossil fuel industry involvement in medical research, leading to fresh calls for academics and publishing companies to cut ties with companies.... Read more
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Novel CAR T cell therapy obe-cel demonstrates high response rates in adult patients with advanced B-cell ALLPatients with relapsed or refractory CD19-positive B-cell acute lymphoblastic leukemia (ALL) who were treated with the novel anti-CD19 chimeric antigen receptor (CAR) T cell therapy, obecabtagene autoleucel (obe-cel), experienced high response rates and most did not need a subsequent stem cell transplant (SCT), according to results from the Phase Ib/II... Read more
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Lipid lifelines: The metabolic shifts behind regenerationRegenerating tissues following injury is a demanding task most multicellular organisms master to different levels. In order to better understand the mechanisms common to many species behind tissue regeneration, researchers from the Paul Langerhans Institute Dresden and the BIOTEC (TU Dresden), decided to examine changes in systemic metabolism during regeneration.... Read more
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Hyperbaric oxygen might be effective treatment for PTSD—here's how it worksPost-traumatic stress disorder (PTSD) is common in military veterans but can affect anyone who has suffered or witnessed an extreme physical or emotional event, and it is very hard to treat. More than two-thirds of people fail to respond to treatment with drugs and therapy. Novel treatments are urgently needed.... Read more
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Researchers of tobacco, alcohol and ultra-processed foods face threats and intimidation: New studyCancer, heart disease, chronic respiratory conditions, diabetes and stroke now account for nearly three-quarters of all deaths globally. Investigating the causes of these diseases has never been more crucial for public health.... Read more
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Cellular traffic congestion in chronic diseases suggests new therapeutic targetsChronic diseases like type 2 diabetes and inflammatory disorders have a huge impact on humanity. They are a leading cause of disease burden and deaths around the globe, are physically and economically taxing, and the number of people with such diseases is growing.... Read more
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Gene therapy shows promise for improving placental functionA gene therapy approach to boosting the placenta is safe in monkeys, according to a new, short-term study, bringing the potential treatment closer to improving birthweights of human babies and sparing them the complications of an early birth and developmental difficulties later in life.... Read more
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New study reveals intimidation tactics against researchers by tobacco, ultra-processed food and alcohol sectorsNew research from the University of Bath shows researchers in the tobacco, ultra-processed food (UPF) and alcohol sectors are frequently targeted with identical intimidation tactics. The most common method used by corporations or their proxies is public discreditation.... Read more
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Adapted nominal group technique effectively builds consensus on health care priorities for older adults, study findsThe participatory research approach is an important tool of family medicine and primary health care research. However, standard consensus methods like the Delphi and nominal group techniques can be time-consuming and may not represent a broad range of opinions.... Read more
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Making pediatric health equity research truly equitable: An EDI review processA burgeoning number of studies are examining pediatric health equity, diversity, and inclusion (EDI). But if not done right, health equity research can do a disservice, perpetuating biases and wrong assumptions that actually exacerbate inequities.... Read more
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Researchers call for inclusive cancer trials and treatments to address overlooked source of structural racismResearchers from Harvard University and Queen Mary University of London have proposed policy changes in cancer care to take account of a common genetic variation.... Read more
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Coffee drinking habits may greatly impact makeup of gut biome, research suggestsA large international team of medical researchers has found that people who drink coffee regularly have much more of one type of gut bacteria than people who do not. In their study, published in the journal Nature Microbiology, the group analyzed stool and blood samples from a large number of... Read more
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Why is it so difficult to make a new antibiotic?The discovery of antibiotics is one of the greatest medical breakthroughs of the 20th century. Before antibiotics, childbirth, a urinary tract infection, or a simple cut could lead to death from infection.... Read more
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Georgia lawmakers consider funding research on how psychedelics might help veteransA bipartisan panel of Georgia lawmakers on Wednesday endorsed a plan recommending the state spend up to $5 million studying the effects of ecstasy, psychedelic mushrooms and other mind-altering drugs on mental health treatments for military veterans.... Read more
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Social connections change our microbiomes, study of isolated villages suggestsFriends tend to share common interests, tastes, lifestyles, and other traits, but a new Yale-led study demonstrates that similarities among buddies can also include the makeup of the microbes lining their guts.... Read more