Scientists capture HIV-1 viral cores entering the nucleus in unprecedented detail

In a recent landmark study, scientists have unveiled how HIV-1 penetrates the cell’s nuclear barrier—a discovery that could reshape antiviral strategies. The research, led by Professor Peijun Zhang, eBIC director at Diamond, used cutting-edge cryo-electron microscopy to capture HIV-1 viral cores in the process of nuclear import—an elusive but critical step in the virus’s life cycle.

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