Scientists find cells that know when, where and how to grow teeth

Tooth development is a dynamic process that involves the stages of the bud, the cap, and the bell, followed by root development and subsequent tooth formation. Processes such as the bud-to-cap transition are mediated by epithelial-mesenchymal interactions. In addition, the position of a cell in a developing embryo determines its fate due to the relative differences in concentration of signaling molecules and growth factors.

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