Stem cell scientists unlock blueprint for lab-grown kidney cells with preclinical value

In the lab, it’s easier to grow simple balls of cells than complex asymmetrical structures with two distinct ends—like the one million filtering units—nephrons—that make up a human kidney. But new research unveils a blueprint that makes it possible to generate specific kidney cell types on demand—cells that hold immense value for preclinical studies of new therapeutics, congenital kidney diseases, and drug-induced nephrotoxicity.

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