Exocyst complex failure in mice reveals a cause of female infertility

Communication between oocytes and granulosa cells is essential for oocyte formation, dormancy, reawakening, and maturation. Researchers at University of Tsukuba have demonstrated that a protein complex called the exocyst complex plays a crucial role in this process. Using a mouse model, their investigations revealed that a deficiency in this complex causes female infertility.

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