Computational analysis links blood RNA patterns to ALS diagnosis and prognosis

Amyotrophic lateral sclerosis (ALS) is a disease that destroys the nerves necessary for movement. About 30,000 people in the United States are affected, and doctors still don’t know what causes it. To lay the groundwork for better tests, Thomas Jefferson University researchers Phillipe Loher, Eric Londin, Ph.D., and Isidore Rigoutsos, Ph.D. are taking a computational biology approach to see how ALS affects molecules in the blood.

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