Researchers at Children’s Hospital of Philadelphia (CHOP) unveiled a novel antibody-drug conjugate (ADC) that shows striking efficacy against cancers that express the anaplastic lymphoma kinase (ALK) protein on the cancer cell surface. The therapy, named CDX0239-PBD, achieved complete and lasting tumor responses in preclinical models of neuroblastoma, rhabdomyosarcoma and colorectal carcinoma, according to findings published in Nature Communications.
Promising preclinical therapy exploits ALK protein to selectively destroy tumors while sparing healthy cells
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HighlightsFree Dark Web Monitoring Stamps the $17 Million Credentials Markets
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HighlightsSmart buildings: What happens to our free will when tech makes choices for us?
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AppsScreenshots have generated new forms of storytelling, from Twitter fan fiction to desktop film
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HighlightsDarknet markets generate millions in revenue selling stolen personal data, supply chain study finds
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SecurityPrivacy violations undermine the trustworthiness of the Tim Hortons brand
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Featured HeadlinesWhy Tesla’s Autopilot crashes spurred the feds to investigate driver-assist technologies – and what that means for the future of self-driving cars
